Bankstown's unbeaten run in 2021 came to an end after one brilliant century was matched by an equally sensational knock in a quality McDonald's Women's Premier Cricket shoot-out with Sydney on Sunday.

The Sportys scored 3-246 from their 50 overs on the back of Madeline Penna's classy 117 and contributions from Katie Mack (33), Tahlia Dunne (38) and Angelina Genford (39 not out).

It's a total that would win most games – and Bankstown had every right to think it was well on track when the Tigers lost their first two wickets for just 17.

But a superb innings from top order batter Jodie Hicks turned the game on its head.

She made a run-a-ball 120 not out to drag the competition leaders back into the contest and – with help from Kira Churchland (41) and Anita Handono (39*) – onto victory by six wickets.

It brought an end to Bankstown's run of four straight wins dating back to the resumption of the competition in January.

In other matches, Penrith upset St George-Sutherland, Universities defeated Campbelltown-Camden and Parramatta overcame Gordon.

But there was no doubting the star of the weekend – 24-year-old Hicks, who scored her first century at grade level.

"I was just looking to face as many balls as I could and to build some good partnerships so we could take the game deep," she explained.  

"The century would have meant nothing if we didn't win."  

Six spots separated St George-Sutherland and Penrith on the table at the start of their game at Glenn McGrath Oval.

And for a while it looked as though the match would stick to the form guide as Penrith slumped to 3-24 chasing 161.

Lisa Griffith took it upon herself to pull the Lady Cats back from the brink, making a patient 72 and garnering terrific support from Kelsey Myers (20) and Eloise Williams (20 not out).

Penrith reached its destination with four wickets and three overs to spare.

Universities lost just the one wicket chasing Campbelltown-Camden's below par 56 and Parramatta was too good for Gordon.

Two Blues skipper Hayley Silver-Holmes had a day out, scoring an undefeated 93 before taking 3-6.