Veteran Fairfield-Liverpool skipper Jarrad Burke will rack up First Grade game number 400 when a quality round of McDonald's Men's Premier Cricket gets underway on Saturday.

Burke will become just the sixth player to reach the milestone when he leads the Lions against  Blacktown Mounties at Rosedale Oval.

It's the feature of a top-shelf round of matches, with four teams inside the top six meeting.

Ladder leader Manly-Warringah is at home to fourth-placed Randwick-Petersham while Sydney University (2nd) take on Northern District (5th) at Uni Oval.

But there's no doubt where the main spotlight will focus – on the indefatigable Burke.

The 37-year-old debuted as a 17-year-old in 2000 for Penrith and has gone on to rack up 21 consecutive seasons for the Panthers, Campbelltown-Camden, Bankstown and now Fairfield-Liverpool. 

"I can’t believe I've reached 400…I'm  a bit surprised the body's held up that long to be honest," Burke said with a laugh.

"My debut was a long time ago (2000) but I still love it as much as I ever did.

"I wake up every Saturday and pull the blinds open and hope it's sunny outside."

Burke has scored 10,647 runs at 30.22 (18 centuries) and captured 651 wickets at 21.70 (13 five-fors) with his left-arm orthodox spin.

He is just one of five players to score 10,000 runs and take 600 wickets and is 28 runs away from replacing Brian Booth in 20th position on the all-time grade run-scorers' list.    

Burke rates the premiership he won with Bankstown in 2006/7 as a career highlight and hopes to add at least one more title to his collection before retirement.

Not that he is contemplating the R word just yet.

"If I'm still enjoying it and contributing then I will play as long as I can," Burke said.

"I'm not really into milestones - I play to win competitions – but it is a decent achievement.

"I really think this side can do something this season and into the future and I want to be part of it."

While the attention will be on Burke and the two top-of-the-table clashes, at the other end of the ladder one team will get its first win of the year when Mosman host Campbelltown-Camden at Allan Border Oval.

Both sides have recorded four losses and a draw after five rounds and will be desperate to climb away from the competition cellar.

Schedule and teams click here

Live streamed matches click here

*matches with a triangle next to UPCOMING in the top righthand corner are live streamed.